At close, the Sensex was down 421.82 points or 1.10% at 38071.13, and the Nifty was down 97.60 points or 0.86% at 11202.90 as investors booked profit in the recent outperformers. Reliance Industries Ltd was the top Sensex loser followed by M&M, HCL Tech, and Nestle. While the gainers were IndusInd Bank, Tata Steel, UltraTech Cement, Sun Pharma, Bajaj Finance, and L&T.About 1359 shares have advanced, 1300 shares declined, and 129 shares are unchanged. Nifty Pharma gained 3 per cent, Nifty PSU Bank index gained over 1.5 per cent. Nifty Auto fell over 1 per cent. Most of the sectoral indices ended in the red, while Nifty Pharma, Nifty Metal, and Nifty PSU Bank were the top sectoral gainers.BSE MidCap index gained 0.68 per cent. BSE SmallCap gained over 0.4 per cent.