At close, the Sensex was down 465.01 points or 0.95% at 48253.51, and the Nifty was down 137.70 points or 0.94% at 14496.50 as an unwavering rise in Covid-19 cases and a slower-than-expected pace of vaccination worried investors on Dalal Street. Reliance Industries was the top loser followed by Sun Pharma, Dr Reddy’s, HDFC Bank, and HDFC. While gainers include ONGC, Bajaj Finance, and TCS. About 1374 shares have advanced, 1534 shares declined, and 169 shares are unchanged. The Nifty PSU Bank index gained 3.5 percent, The Nifty Pharma index, on the contrary, was down 2 percent. The S&P BSE MidCap and SmallCap indices each ended about half a percent lower today.