At the close, the Sensex was down 1,375.27 points or 4.61% at 28440.32, and the Nifty was down 379.15 points or 4.38% at 8281.10. Nestle, Cipla, Tech Mahindra, Axis Bank and Dr Reddys Labs were major gainers on the Nifty, while Bajaj Finance, HDFC, Kotak Mahindra Bank, Tata Steel and HDFC Bank were among major losers on the Nifty. About 924 shares have advanced, 1320 shares declined, and 168 shares are unchanged. Nifty Bank and Nifty Auto indexes were also down over 6 per cent each. On the other hand, Nifty Pharma index ticked up 1 per cent.BSE Midcap and Smallcap indices shed 1.7-2 per cent.